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2024年2月22日发(作者:head first python pdf)
吉西他滨联合卡铂治疗复发性卵巢癌
【摘要】目的:评估吉西他滨联合铂类治疗复发性卵巢癌的疗效及毒性。方法:31例复发性卵巢癌化疗方案:第1、8天吉西他滨1000 mg/m2静注;cbp浓度-时间曲线下面积(auc)=5,第l天静脉滴注;21 d为一疗程。结果:31例患者总有效率64.5%,其中5例cr(16.1%),15例pr(48.4%)。中位无进展生存期为7.2个月。毒性主要为白细胞减少和血小板减少。结论:吉西他滨联合卡铂是治疗复发性卵巢癌的有效方案,毒性可以耐受。
【关键词】卵巢肿瘤;肿瘤复发;吉西他滨;卡铂
gemcitabine combined with carboplatin in treatment of
recurrent ovarian cancer/chen li-hui,wu jing,luo ju-hong,et al.//medical innovation of china,2012,9(11):051-052
【abstract】objective:to evaluate the efficacy and
toxicities of gemcitabine combined with carboplatin in
treatment of recurrent ovaria s:thirty-one
patients with recurrent ovarian carcinoma received
gemcitabine(1000 mg/m2) combined with carboplatin was
intravenously administered on day 1 with area under the
concentration-time curve of 5,each course of treatment lasted
for 21 d.results:of 31 patients,there were 5(16.1%)complete
responses and 15 (48.4%) partial responses,for an overall
response rate of 64.5%,the mean progression free survival
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